Day 15, you will take 1 viramune tablet 2 times a day.
Information about Viramune.
Because virus resistant to all available NNRTIs can be selected rapidly during failure of a nevirapine-containing regimenit is important to assess patient motivation and discuss possible side effects and strategies for their management before treatment with nevirapine is initiated.
A clinically not relevant increase in the apparent clearance of nevirapineby 9compared to historical data was reported.
Results of in vitro studies showed a weak antagonism of nevirapine by adefovirsee section 5.1this has not been confirmed in clinical trials and reduced efficacy is not expectedAdefovir did not influence any of the common CYP isoforms known to be involved in human drug metabolism and is excreted renallyNo clinically relevant drug-drug interaction is expected.
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Hormonal methods of birth control other than Depo-medroxyprogesterone acetateDMPAshould not be used as the sole method of contraception in women taking Viramunesince nevirapine might lower the plasma concentrations of these medicinal productsFor this reasonand to reduce the risk of HIV transmissionbarrier contraceptione.gcondomsis recommendedAdditionallywhen postmenopausal hormone therapy is used during administration of nevirapineits therapeutic effect should be monitored.
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john s wort is expected to substantially decrease nnrti concentrations and may result in sub-optimal levels of viramune and lead to loss of virologic response and possible resistance to viramune or to the class of nnrtis.
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