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Glycopotin IIb/IIIa Inhibitos: ATOLIP CV should b usd with caution in patints whciv concomitant glycopotin IIb/IIIa inhibitos.
Poton Pump Inhibitos : Avoid concomitant us ATOLIP CV with ompazol sompazol. In clinical studis, ompazol was shown tduc th antiplatlt activity clopidogl whn givn concomitantly 12 hous apat. A high dos gimn clopidogl concomitantly administd with ompazol incass antiplatlt spons; an appopiat dos gimn has not bn stablishd. A simila duction in antiplatlt activity was obsvd with sompazol whn givn concomitantly with clopidogl. Consid using anoth acid-ducing agnt with minimal nCYP2C19 inhibitoy ct on th omation clopidogl activ mtabolit. Dxlansopazol, lansopazol and pantopazol had lss ct on th antiplatlt activity clopidogl than did ompazol sompazol.
Clopidogl is a thinopyidin class inhibitP2Y12 adnosin diphosphat (ADP) platlt cptos. It is an inhibitplatlt activation and agggation though th ivsibl binding its activ mtabolit tth P2Y12 class ADP cptos on platlts.
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