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Fenofibric acid is known to be substantially excreted by the kidneyand the risk of adverse reactions to this drug may be greater in patients with impaired renal functionFenofibric acid exposure is not influenced by ageSince elderly patients have a higher incidence of renal impairmentdose selection for the elderly should be made on the basis of renal functionsee DOSAGE AND ADMINISTRATION and CLINICAL PHARMACOLOGYElderly patients with normal renal function should require no dose modificationsConsider monitoring renal function in elderly patients taking TRICOR.
Upon multiple dosing of fenofibratefenofibric acid steady state is achieved within 5 daysPlasma concentrations of fenofibric acid at steady state are approximately double of those following a single doseSerum protein binding was approximately 99in normal and hyperlipidemic subjects.
TriCor should only be used when other measuressuch as diet and exercisehave not been enoughTriCor is a prescription medicine used along with diet in adults to lower triglyceridestotal cholesteroland LDLbadcholesteroland to increase HDLgoodcholesterolTriCor is also used along with diet in adults to lower severely high triglyceridesImproving blood sugar control in certain people with diabetes may prevent the need for cholesterol drug therapyTriCor was not shown to reduce the risk of having heart problems in patients with type 2 diabetes.
No pharmacokinetic studies have been conducted in patientswith hepatic impairment.
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