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Patients with underlying cardiovascular risk factors may be at higher riskincluding people taking any medicines known to prolong the QT intervalDomperidone should not be used with medicines that prolong QT interval or with medicines that inhibit CYP3A4Additionallydomperidone should not be used in patients with moderate to severe hepatic impairment.
Motilium should be used at the lowest effective dose for the shortest duration necessary to control nausea and vomiting.
Motiliuma heartburn and anti-nausea drug taken by millions of peopleshould be restricted because of the risk of fatal heart problemsregulator says.
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