Acute mania trials have demonstrated superior efficacy of olanzapine to placebo, equal or superior efficacy to valproate and superior efficacy in combination therapy with lithium or valproate compared to mood stabilizer monotherapy.

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Information about Olanzapine.

Olanzapine may be . used aspart of a combination therapyThis means you may need to take it with other medicationssuch as lithiumvalproateor fluoxetine.

Stop using olanzapine and call your doctor at once if you have any of these serious side effects:

Possibility of suicide attempt is inherent in schizophrenia and in bipolar I disorderand close supervision of high-risk patients should accompany drug therapywhen using in combination with fluoxetinealso refer to Boxed.

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olanzapine-treated patients had a greater mean hba 1c increase from baseline of 0.