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Frusemide has been shown to impair the metabolism of azathioprine by human hepatic tissue in vitroThe clinical significance is unknown.

If you think there has been an overdosecall your poison control center or get medical care right awayBe ready to tell or show what was takenhow muchand when it happened.

Patients receiving multiple immunosuppressive agents may be at risk of over-immunosuppressiontherefore such therapy should be maintained at the lowest effective level.

IMURAN can cause fetal harm when administered to a pregnant womanIMURAN should not be given during pregnancy without careful weighing of risk versus benefitWhenever possibleuse of IMURAN in pregnant patients should be avoidedThis drug should not be used for treating rheumatoid arthritis in pregnant women12.

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